pentobarbital will reduce the level or result of ritonavir by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Monitor.pentobarbital will lessen the extent or influence of suvorexant by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Monitor. Strong CYP3A4 inducers may possibly decrease suvorexant efficacy; if g